The Toronto Blue Jays will look to draw even at 2-2 in their best-of-seven series when they take on the Seattle Mariners in Game 4 of the American League Championship Series on Thursday. After losing both games in Toronto, the Blue Jays kept the home team winless in the series with a 13-4 win on Wednesday. The Blue Jays (94-68), the top seed in the American League, are 42-42 on the road in 2025, including the postseason. The Mariners (90-72), the third seed, are 53-32 on their home field. Luis Castillo will start for the Seattle, opposed by Max Scherzer of Toronto.

First pitch from T-Mobile Park in Seattle is set for 8:33 p.m. ET. The teams have split the past eight meetings. Seattle is a -128 favorite on the money line (risk $128 to win $100) in the latest Blue Jays vs. Mariners odds from DraftKings Sportsbook, while Toronto is at +107 (risk $100 to win $107). The total number of runs Vegas thinks will be scored, or the over-under, is 7.5 in the latest MLB odds. 

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