Bills vs. Jaguars line, odds: Proven model releases spread pick for 2026 NFL Wild Card Weekend matchup on Sunday

The red-hot third-seeded Jacksonville Jaguars look to win their ninth game in a row when they take on the sixth-seeded Buffalo Bills in a 2026 Wild Card Weekend matchup on Sunday. Buffalo is coming off a 35-8 win over the New York Jets, while Jacksonville defeated Tennessee 41-7 in Week 18. The Bills (12-5), who have won five of the past six games, are 5-3 on the road this season. The Jaguars (13-4), who won the AFC South title, are 7-2 on their home field.

Kickoff from EverBank Stadium in Jacksonville, Fla., is set for 1 p.m. ET on CBS and Paramount+. The all-time series is tied 10-10, but Jacksonville has won both playoff meetings. The Bills are 1.5-point favorites in the latest Bills vs. Jaguars odds, while the over/under for total points scored is 51.5 via DraftKings Sportsbooks. 

Before making any Bills vs. Jaguars picks, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters 2026 NFL Wild Card Weekend on a 53-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Bills vs. Jaguars.

We can tell you it's leaning Under the point total, but also says that one side of the spread hits well over 50% of the time! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Bills vs. Jaguars in 2026 NFL Wild Card Weekend, and which side of the spread hits well over 50% of the time? ... Join SportsLine RIGHT NOW to see which side of the line to back, all from the model that has gone 53-37 on top-rated picks since 2024!

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