Bengals vs. Broncos odds, line: 2025 NFL picks for Week 4 Monday Night Football predictions from proven expert

Teams coming off disappointing weeks look to turn their fortunes around on Monday Night Football when the Cincinnati Bengals clash with the Denver Broncos. The Bengals (2-1), who are tied for first in the AFC North with the Pittsburgh Steelers, are 2-0 against AFC opponents in 2025. The Broncos (1-2), who trail the Chargers by two games, are 1-2 against AFC foes. Jake Browning will start at quarterback for the Bengals in place of Joe Burrow (toe), who could miss the rest of the season. Cincinnati tight end Noah Fant (concussion) is out.

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Kickoff from Empower Field at Mile High in Denver is set for 8:15 p.m. ET. Denver leads the all-time series 22-12, but Cincinnati earned a 30-24 win in overtime last year. The Broncos are 7.5-point and -463 money-line favorites in the latest Bengals vs. Broncos odds, while the over/under for total points scored is 44.5 via SportsLine consensus. 

Before making any Bengals vs. Broncos picks, be sure to check out what SportsLine expert Adam Silverstein has to say.

CBS Sports' managing editor, Silverstein is an expert on college and pro football and is coming off a second straight dominant NFL season. He went 100-75-7 (plus $1,749 for $100 players, every bet one unit) in the 2024 season, bringing his two-year run to 188-138-16 (plus $3,564).

Anyone following him has seen impressive returns. He especially has the pulse of the Denver Broncos. In his last 19 selections involving the Broncos, he is an incredible 17-2 (+1470)!

Now Silverstein has zeroed in on Bengals vs. Broncos. 

He's leaning Over on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Broncos vs. Bengals, and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the spread to jump on, all from the expert who is on a sizzling 17-2 run on picks involving the Broncos!

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