Bears vs. 49ers prediction, line, odds: Proven model releases spread pick for 2025 NFL Week 17 matchup on 'Sunday Night Football'

A Week 17 NFL 'Sunday Night Football' contest has a pair of NFC playoff teams meeting as the Chicago Bears visit the San Francisco 49ers. Chicago (11-4) is coming off a 22-16 victory over Green Bay on Saturday. San Francisco (11-4) enters in off a 48-27 win over Indianapolis on Monday. These teams have alternated wins and losses over their last eight meetings, with San Fran prevailing in the last matchup.

Kickoff is at 8:20 p.m. ET from Levi's Stadium in Santa Clara, Calif. The latest 49ers vs. Bears odds have San Francisco as 3-point home favorites, while the over/under for total points scored is 52.5 via SportsLine consensus.

Before making any Bears vs. 49ers picks, or 2025 NFL Week 17 predictions of your own, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 on a 53-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for 49ers vs. Bears on 'Sunday Night Football'.

We can tell you it's leaning Over the point total, but also says that one side of the spread has all of the value! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Bears vs. 49ers in NFL Week 17, and which side of the spread has all of the value? ... Join SportsLine RIGHT NOW to see which side of the 49ers vs. Bears line to back, all from the model that has gone 53-37 on top-rated picks since 2024!

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