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Athletics vs. Nationals odds, line, start time, picks, best bets for August 7 matchup from proven model

SportsLine's projection model, which is on a 28-23 roll on top-rated MLB money-line picks, has locked in its MLB picks for the Athletics vs. Washington matchup on Thursday

ByUpdated: Aug 07, 2025 1:49PM UTC . 2 min read

A series win will be on the line when the Athletics battle the Washington Nationals in an interleague matchup on Thursday afternoon. The Athletics (50-66), who have won six of their last 10 games, are 27-32 on the road this season. The Nationals (45-68), who have lost six of seven, are 22-35 on their home field in 2025.

First pitch from Nationals Park in Washington is set for 12:05 p.m. ET. The Nationals have won seven of the last 10 meetings with the Athletics. The Athletics are a -137 favorite on the money line (risk $137 to win $100) in the latest Athletics vs. Nationals odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over-under, is 9 in the latest MLB odds. 

Before you make any Athletics vs. Nationals picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 20 of the 2025 MLB season a profitable 28-23 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning nearly 60 units of profit. Anybody following could have seen strong returns!

The model has simulated Athletics vs. Nationals 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has all the value!

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Daniel Kohn

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