The Houston Astros (52-34) go on the road to close out their series against the Colorado Rockies (19-67) on Thursday. Houston picked up wins in the first two series contests, with a 5-2 victory over Colorado on Wednesday evening. Kyle Freeland (1-9, 5.56 ERA) takes the mound for the Rockies. Brandon Walter (1-1, 3.34 ERA) gets the start for Houston. 

First pitch is scheduled for 3:10 p.m. ET at Coors Field in Colorado. The Astros are the -190 money-line favorites (bet $190 to win $100) in the latest Astros vs. Rockies odds, while the Rockies are +160 underdogs (bet $100 to win $160). The over/under for total runs scored is 11 in the latest MLB odds. 

Before you make any Astros vs. Rockies picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 15 of the 2025 MLB season on a profitable 39-30 run on top-rated MLB sides picks. It has excelled making home run prop picks this season, returning more than 24 units of profit. Anybody following could have seen strong returns!

The model has simulated Astros vs. Rockies 10,000 times and the results are in. We can tell you the model is going Under on the run total, and it also says one side of the money line has all the value!

Who wins Astros vs. Rockies, and which side of the money line has all the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 39-30 roll on top-rated MLB picks!