Arkansas vs. Alabama odds, prediction: 2026 Southeastern Conference men's college basketball picks from proven model

Two AP top-25 teams battle when the No. 20 Arkansas Razorbacks meet the No. 25 Alabama Crimson Tide in a key Southeastern Conference matchup on Wednesday. Arkansas is coming off an 88-75 win over Auburn on Saturday, while Alabama stopped South Carolina 89-75 that same day. The Razorbacks (19-6, 9-3 SEC), who are second in the conference, are 4-3 on the road this season. The Crimson Tide (18-7, 8-4 SEC), who are tied for third in the league, are 9-3 on their home floor.

Tip-off from Coleman Coliseum in Tuscaloosa, Ala., is set for 7 p.m. ET. Arkansas leads the all-time series 36-35, but Alabama holds a 23-8 edge in games played at Tuscaloosa. Alabama is a 4.5-point favorite in the latest Arkansas vs. Alabama odds from DraftKings Sportsbook, while the over/under for total points scored is 183.5. 

Before making any Arkansas vs. Alabama picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 16 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 13-7 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Arkansas vs. Alabama 10,000 times and the results are in. The model is leaning Under, and it also says one side of the spread hits nearly 70% of the time!

So who wins Arkansas vs. Alabama, and which side of the spread hits nearly 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!