The 2024-25 college basketball season continues on Monday and the action for the night will wrap up with a high-profile Big 12 matchup between the Arizona Wildcats and the Iowa State Cyclones. Arizona will host and is 13-6 on the season with a 7-1 record in conference play while No. 3 Iowa State is 17-2 overall and is also 7-1 in the league. Both of these programs were No. 2 seeds in last year's NCAA tournament and were knocked out in the Sweet 16 and now the two powers will begin a new era as rivals in the Big 12 after Arizona left the Pac-12 this offseason.

Tipoff from the McKale Memorial Center in Tucson, Ariz., is set for 10:30 p.m. ET. The Wildcats are favored by 2.5 points in the latest Arizona vs. Iowa State odds from SportsLine consensus, and the over/under is 152.5 points.

Before entering any Iowa State vs. Arizona picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 13 of the 2024-25 season on a 202-142 roll (+2468) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Arizona vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits over 50% of the time!

So who wins Iowa State vs. Arizona, and which side of the spread hits over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!