Raymond James Stadium hosts a non-conference matchup between the South Florida Bulls and the No. 10 Alabama Crimson Tide at 3:30 p.m. ET on Saturday. For this game, SportsLine consensus lists the Crimson Tide as 34-point favorites, while the over/under is set at 61 (see up-to-date odds for every game this week on our college football odds page). Alabama is expected to turn to Notre Dame transfer Tyler Buchner at quarterback in place of Jalen Milroe. 

Before making any Alabama vs. South Florida picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of nearly $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Alabama has the physical and athletic advantage in this matchup. The Crimson Tide are averaging 2.9 yards per carry allowed through two games, with opponents also averaging only 6.6 yards per pass attempt. Alabama is yielding only 38% third down efficiency, and dating back to 2022, the Crimson Tide were near the top of the country in points allowed (18.0 per game) and total yards allowed (311.3 per game). 

The model also knows South Florida is off to a strong start on offense. The Bulls are averaging 31.0 points per game this season, and South Florida is in the top three of the AAC with 441.0 total yards per contest. USF is also leading the conference with 241.0 rushing yards per game, and QB Byrum Brown leads the AAC with eight total touchdowns in two games.

Now, it has set its sights on Alabama vs. South Florida. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in nearly 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Alabama vs. South Florida? And which side of the spread hits in nearly 60% of simulations? ... Join SportsLine right now to find out which side of the Alabama vs. South Florida spread you should be all over Saturday, all from the model that's up nearly $2,500 on top-rated CFB spread picks since its inception!