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Alabama vs. Oklahoma odds, line: 2025 college football picks for Week 12 predictions from proven model

SportsLine's model has locked in its best bets for Saturday's SEC matchup between Oklahoma and Alabama

By@Daniel_LewisSLPublished: Nov 15, 2025 6:10PM UTC . 2 min read

No. 4 Alabama (7-1) hosts No. 11 Oklahoma (5-2) in an important SEC showdown on Saturday. Kickoff is at 3:30 p.m. ET. The latest Alabama vs. Oklahoma odds list the Tide as 6.5-point favorites, with the over/under at 45.5.

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Before making any Oklahoma vs. Alabama picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anyone following could have seen impressive returns.

The model has simulated Oklahoma vs. Alabama 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread is the better value!

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