2026 American Express odds, predictions: Top picks, props and analysis for this week's event in La Quinta, Calif.

Scottie Scheffler makes his season debut as the odds-on favorite to win the 2026 PGA American Express Tournament. The world's top-ranked golfer is looking to win his 20th PGA tournament since turning pro in 2018. Scheffler, 29, last won at the Procore Championship last September in Scottsdale, Ariz. He won by one stroke over fellow American Ben Griffin.

This year's event gets underway at 11:30 a.m. ET from La Quinta Country Club in La Quinta, Calif. The tournament will begin on a par-72 course measuring 7,210 yards. Scheffler is the +300 favorite (risk $100 to win $300) at FanDuel Sportsbook. Other favorites include Ben Griffin at +2000 and Sam Burns and Russell Henley, both at +2200.

Before making any 2026 American Express picks, you NEED to see the predictions and best bets from elite golf expert Brady Kannon.

Kannon is an elite golfing handicapper with more than 30 years of experience in the industry. He's hit eight major outright winners since 2013. In the fall of 2022, he hit outright winners in three consecutive weeks: Russell Henley (40-1), Tony Finau (18-1) and Adam Svensson (150-1). 

Last season, he hit Hideki Matsuyama (22-1), Harris English (110-1), Ludvig Aberg (25-1), and Ben Griffin/Andrew Novak (25-1) in New Orleans. Since joining SportsLine, he's 19-13-4 on head-to-head bets. Anyone who followed his lead could have been WAY UP!

Now, Kannon has been digging into this week's field to find the best betting value and just locked in his best bets to back. He's fading Wyndham Clark (80-1) in both the outright market and head-to-heads. 

Kannon has revealed his best bet, and it's a surprising golfer who returns nearly 100-1 and is a perfect course fit!

What are the best bets for The American Express 2026, and which massive longshot should you back? ... Join SportsLine right now to see Brady Kannon's best picks, all from the expert who nailed four winners last season!