Houston and Minnesota are on a bye in Week 6, and the Giants and Eagles played Thursday night. We also have the Lions and Chiefs on Sunday night, and two Monday night games with Buffalo at Atlanta and Chicago at Washington.

We're down a lot of star players for the main DFS slate on DraftKings and FanDuel, which isn't ideal. But we can still set some fun lineups.

Some of my favorite matchups to target for Week 6 include San Francisco at Tampa Bay and Dallas at Carolina. And I also like the Rams (at BAL), Packers (vs. CIN), and Patriots (at NO), given their opponents.

Every Friday, come here to see the players who I'm targeting for each site. We'll give you lineup suggestions and go over what values make sense to build a team that will hopefully be profitable.

I hope by the time Monday gets here, we're all celebrating in a big way. But, just remember, even if you only win a small amount, this is the start of building your bankroll for a long season.

Which QB-WR combination is worth locking into DraftKings lineups? And which running back is worth using in lineups on both sites? ... Join SportsLine here to see Jamey Eisenberg's Week 6 DFS lineups!