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2025 Week 10 DFS lineups: Jamey Eisenberg's million-dollar tournament plays for DraftKings and FanDuel

Eisenberg, the CBS Sports Fantasy expert, goes through his DFS lineup decisions for Week 10 GPP tournaments

ByJameyEisenbergUpdated: Nov 07, 2025 9:20PM UTC . 2 min read

This isn't the most ideal DFS week. We're not only down the offensive stars from Cincinnati, Dallas, Kansas City, and Tennessee -- if you want to include the Titans in this discussion -- but we also can't target two of our favorite matchups with the Bengals and Cowboys. Those defenses bleed Fantasy points.

Along with that, we have another Sunday morning game in Berlin (ATL-IND), which is not on the main slate, and our usual Sunday night game (PIT-LAC) and Monday night game (PHI-GB). That's a ton of talent not available for us to use.

That said, we can still have some fun. Did you think we were taking a week off from setting lineups on DraftKings and FanDuel? No way.

Every Friday, come here to see the players who I'm targeting for each site. We'll give you lineup suggestions and go over what values make sense to build a team that will hopefully be profitable.

I hope by the time Monday gets here, we're all celebrating in a big way. But, just remember, even if you only win a small amount, this is the start of building your bankroll for a long season.

Which QB-WR combination is worth locking into DraftKings lineups? And which running back is worth using on each site? ... Join SportsLine here to see Jamey Eisenberg's Week 10 DFS lineups!

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