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2025 NFL Week 3 Chiefs vs. Giants line, odds: Expert reveals pick for matchup on Sunday Night Football

R.J. White, who is on a 46-22 roll on New York Giants games, has released his best bets for the Week 3 Kansas City Chiefs vs. New York Giants SNF matchup

ByPublished: Sep 21, 2025 11:03PM UTC . 3 min read

Teams looking to avoid a 0-3 start to the season clash when the Kansas City Chiefs take on the New York Giants on Sunday Night Football. Kansas City is coming off a 20-17 loss to the Philadelphia Eagles, while New York dropped a 40-37 overtime decision at Dallas. The Chiefs (0-2), who have been to three consecutive Super Bowls and five of the past six, are 7-3 on the road since the start of 2024. The Giants (0-2), who have made the playoffs just twice since winning Super Bowl XLVI in 2011, were 1-8 on their home field last season. The Chiefs are 0-7 all-time in road games versus the Giants.

Kickoff from MetLife Stadium in East Rutherford, N.J., is set for 8:20 p.m. ET. The Giants lead the all-time series 11-4, but Kansas City has won two of the past three meetings. The Chiefs are 6-point favorites in the latest Chiefs vs. Giants odds, while the over/under for total points scored is 44.5. Kansas City is at -319 on the money line (risk $319 to win $100), while New York is at +255 (risk $100 to win $255).

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Before making any Chiefs vs. Giants picks, you NEED to see which side SportsLine NFL expert R.J. White is on, considering his mastery of picks involving the Giants.

White, a Fantasy and gambling editor for CBS Sports, consistently crushes against-the-spread picks and has gone 718-623-37 on his ATS picks from 2017-24, which returned more than $3,200 to $100 players. He is an OUTSTANDING 46-22 (+2105) on his last 68 picks in games involving the Giants! Anyone who has followed him is WAY up!

Now, White has locked in another confident against-the-spread pick for Chiefs vs. Giants.

We can tell you he's leaning Under on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

So who wins Chiefs vs. Giants on Sunday Night Football, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine right now to see which side of the Chiefs vs. Giants spread to back, all from the expert who is a blistering 46-22 on picks involving the Giants!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW. 

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Daniel Kohn

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