2025 NFL Week 17 Rams vs. Falcons line, odds: Expert reveals pick for matchup on Monday Night Football

The Los Angeles Rams look to stay in the race for the NFC West championship when they battle the Atlanta Falcons in a key NFC matchup on Monday Night Football. Los Angeles is coming off a 38-37 overtime loss to the Seattle Seahawks in Week 16, while Atlanta downed Arizona 26-19. The Rams (11-4), who are 6-4 within the conference, are 5-3 on the road this season. The Falcons (6-9), who are third in the NFC South, are 5-5 in the conference and 2-4 on their home field in 2025.

Kickoff from Mercedes-Benz Stadium in Atlanta is set for 8:15 p.m. ET. The Rams lead the all-time series 49-30-2, including wins in each of the last two meetings. Los Angeles is an 8-point favorite in the latest Rams vs. Falcons odds, while the over/under for total points scored is set at 49.5. The Rams are -459 favorites on the money line (risk $459 to win $100).

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW. 

Before making any Rams vs. Falcons picks, you NEED to see which side SportsLine NFL expert Larry Hartstein is on, considering his mastery of Rams picks.

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. Hartstein tied for 52nd place (out of 1,598 entries) in the 2022 Westgate Las Vegas SuperContest, going 53-34-3 ATS. He is coming off a down 2024 NFL season at SportsLine that puts him at 967-821 all-time on NFL sides and props (plus 13.8 units), including 593-518 ATS. Entering the 2025-26 season, he has been profitable in five of six seasons, going 659-564 ATS (plus $3,556 for $100 players). 

In addition, Hartstein has gone 28-10 on his last 38 picks involving the Rams, returning $1,701. Anyone who has followed him could be way up. Now, Hartstein has zoned in on Rams vs. Falcons.

We can tell you he's leaning Over on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

So who wins Rams vs. Falcons on Monday Night Football, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine right now to see which side of the Rams vs. Falcons spread to back, all from the expert who is a blistering 28-10 in his last 38 Los Angeles Rams picks!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.