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2025 NFL Week 14 odds, score predictions: SportsLine AI reveals picks for every game

SportsLine AI reveals its NFL picks against the spread, over/under and money line for every NFL game in Week 14

ByPublished: Dec 07, 2025 1:45PM UTC . 3 min read

A 14-game slate highlights NFL Week 14, including a number of key divisional matchups. In an important NFC North battle, first place will be on the line when the Chicago Bears visit the Green Bay Packers. The Packers are favored by 6.5 points as Jordan Love of the Packers takes on Caleb Williams and the Chicago Bears, as Chicago is aiming for its sixth straight victory. Rome Odunze (foot) is out for Chicago, while Jayden Reed is questionable to play after being activated off IR.

Another key divisional battle pits the Pittsburgh Steelers (6-6) against the Baltimore Ravens (6-6) with first place on the line. Baltimore has won each of the last two meetings and enters as the 6-point favorite. The Ravens earned a 28-14 win over the Steelers in last year's playoff meeting. Sunday's largest spreads are Saints vs. Buccaneers (-8.5), the Rams (-8.5) vs. Cardinals and the Broncos (-7.5) versus Raiders, as Denver aims for its 10th straight win.

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Before making any Week 14 NFL picks, be sure to check out the NFL score predictions from the SportsLine's self-learning AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data then quantitatively evaluating the strength of the opponents defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see a 5-star rating on an Over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI has nailed more than 2,000 4.5- and 5-star prop picks since the start of the 2023 season! Anyone who has followed it is WAY UP!

After analyzing every game in Week 14, the AI says the Browns (-3.5), who have split their last two games, cover comfortably against the Titans. Quarterback Shedeur Sanders is expected to make another start. in three games, he has completed 31 of 61 passes (50.8%) for 405 yards and two touchdowns with two interceptions.

SportsLine AI rates the Browns as an A+ spread pick and also predicts a 24-15 win on average.

SportsLine AI has generated against the spread, over/under and money-line picks for every game in Week 14! In fact, the AI has generated more than two dozen HIGHLY-COVETED A+ picks! You ABSOLUTELY NEED to see the AI analysis before making any Week 14 NFL bets.

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Daniel Kohn
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