2025 NFL Week 12 Buccaneers vs. Rams line, odds: Expert reveals pick for Sunday Night Football matchup

Division leaders clash when the NFC South-leading Tampa Bay Buccaneers take on the NFC West-leading Los Angeles Rams on Sunday Night Football. Tampa Bay is coming off a 44-32 loss at Buffalo last week, while Los Angeles defeated Seattle 21-19. The Buccaneers (6-4), who have lost two in a row, are 4-2 on the road this season. The Rams (8-2), who have won five consecutive games, are 4-1 on their home field. Chris Godwin (leg) is questionable, while Tristan Wirfs does not carry an injury designation for Tampa.

Kickoff from SoFi Stadium in Inglewood, Calif., is set for 8:20 p.m. ET. The Rams lead the all-time series 19-10, including wins in three of the last four meetings. The Rams are 7-point favorites in the latest Buccaneers vs. Rams odds, while the over/under for total points scored is set at 49.5. The Rams are -368 on the money line (risk $368 to win $100), with Tampa at +290 (risk $100 to win $290). Los Angeles sports at 7-3 against-the-spread this season, while Tampa Bay is 5-5 versus the line.

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW. 

Before making any Buccaneers vs. Rams picks, you NEED to see which side SportsLine NFL expert Larry Hartstein is on, considering his mastery of picks involving the Rams.

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. Hartstein tied for 52nd place (out of 1,598 entries) in the 2022 Westgate Las Vegas SuperContest, going 53-34-3 ATS. He is coming off a down 2024 NFL season at SportsLine that puts him at 967-821 all-time on NFL sides and props (plus 13.8 units), including 593-518 ATS. Entering the 2025-26 season, he has been profitable in five of six seasons, going 659-564 ATS (plus $3,556 for $100 players). 

In addition, Hartstein has gone 26-10 on his last 36 picks involving the Rams, returning more than $1,500. Anyone who has followed him could be WAY UP!

Now, Hartstein has locked in another confident against-the-spread pick for Buccaneers vs. Rams.

We can tell you he's leaning Over on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

So who wins Buccaneers vs. Rams on Sunday Night Football, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine right now to see which side of the Rams vs. Jaguars spread to back, all from the expert who is a blistering 26-10 on picks involving the Rams!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.