2025 NFL Christmas Day parlay, odds, line, spreads: Proven model reveals top parlay picks

Three divisional battles make up the 2025 NFL Christmas Day slate, making it an ideal opportunity to create an NFL parlay. Cowboys vs. Commanders (+6.5) kicks things off at 1 p.m. ET, followed by Lions vs. Vikings (+5.5) at 4:30 p.m. ET, with Chiefs vs. Broncos (-13) at 8:15 p.m. ET putting a bow on the Christmas NFL schedule. A couple of these squads still have playoff implications in their respective games, making them even more appealing to make NFL picks on. Kansas City is used to seeing itself as 13-point favorites, rather than underdogs, as the team could be onto its third quarterback with Gardner Minshew possibly suffering a torn ACL, a week after Patrick Mahomes did the same.

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Teams that are underdogs of at least 13 points this season are 1-10 straight up but 7-4 against the spread. So, backing the Broncos to win on the money line in your Christmas NFL picks but backing the Chiefs ATS could be a route to pursue. There are also NFL player props and over/under predictions that could factor into your Christmas NFL parlay.

Before locking in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 16 on a 52-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

The model has scoured the Week 17 NFL odds and locked in four confident NFL best bets for Christmas Day. If you successfully parlay its sports betting picks, you'd be looking at a massive payout of well over 9-1. 

One pick we'll give away: The model is backing the Over (50.5) to hit in Cowboys vs. Commanders at 1 p.m. ET. SportsLine's simulations forecast the teams combining for 60 points as the Over hits well over 60% of the time.

The model is also backing an NFL player prop that returns plus-money odds! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back on Christmas, and which four picks should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on a 52-37 roll on top-rated NFL picks!

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