The fourth-seeded Indiana Pacers battle the third-seeded New York Knicks in Game 1 of their 2025 NBA Eastern Conference finals matchup on Wednesday. The Pacers (50-32), who were swept in last year's conference finals by Boston, are looking to reach the NBA Finals for the first time since 1999-00. The Knicks (51-31), who last reached the Eastern Conference finals in 1999-00, have not won an NBA title since 1973. The Pacers have won five of the eight previous postseason series between the franchises.

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Tipoff from Madison Square Garden in New York is set for 8 p.m. ET. The Knicks are 4.5-point favorites in the latest Pacers vs. Knicks odds, while the over/under for total points scored is 221.5. New York is at -190 on the money line (risk $190 to win $100), while Indiana is at +158 (risk $100 to win $158).

Before making any Pacers vs. Knicks picks, be sure to see the NBA predictions from legendary handicapper Bruce Marshall.

An in-demand guest on numerous sports talk radio and TV shows across the country, Marshall's vast array of editorial work has been featured in the Las Vegas Review-Journal, the New York Post and many other outlets. He has won various handicapping titles and also is working on several book projects. Marshall has crushed his NBA picks this season for SportsLine members, entering this matchup on a 131-101-2 run in his last 234 NBA picks that has returned nearly $1,800 for $100 players.

Marshall also has a strong read on the Pacers. He is an outstanding 56-27 (+2624) on his last 83 picks in games involving the Indiana Pacers. Anybody following could be WAY up!

Marshall is going Over on the total, and he's also found a critical X-factor that makes one side of the spread a must-back! Be sure to see what it is before locking in any picks of your own.

Who wins Pacers vs. Knicks, and what critical X-factor makes one side a must-back? Join SportsLine right now to see which side of the Pacers vs. Knicks spread you need to jump on, all from the expert who has returned nearly $2,000 for $100 players in his last 234 NBA picks!

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