Teams looking to stay perfect meet in non-conference action when the Indiana State Sycamores battle the 22nd-ranked Indiana Hoosiers on Friday night. Indiana State downed Eastren Illinois 38-14 on Saturday, while Indiana cruised past Kennesaw State 56-9. The Sycamores (2-0), who finished tied for sixth in the 1-AA Missouri Valley Football Conference and 4-8 overall, were 0-6 on the road last year. The Hoosiers (2-0), who tied for second at 8-1 and were 11-2 overall in 2024, are 10-0 at home since the start of last season.

Kickoff from Memorial Stadium in Bloomington, Ind., is set for 6:30 p.m. ET. Indiana leads the all-time series 7-0, last meeting in 2023. Indiana is a 47.5-point favorite in the latest Indiana State vs. Indiana odds, while the over/under for total points scored is 59.5. 

Before locking in any Indiana State vs. Indiana bets or predictions, check out what SportsLine college football expert Micah Roberts has to say, given his mastery of picks in games involving Indiana.

Micah Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos' book director.  Most importantly, Roberts has a read on the pulse of Indiana. He is 9-1 (+795) on his last 10 against-the-spread picks in games involving Indiana!   Anybody following is WAY UP!

Now, Roberts has locked in another confident against-the-spread pick for Indiana State vs. Indiana.

We can tell you he's leaning Over on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

So who wins Indiana State vs. Indiana on Friday night, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine right now to see which side of the Indiana State vs. Indiana spread to back, all from the expert who is a blistering 9-1 on picks involving the Hoosiers!