The Week 5 college football schedule is highlighted by the monumental clash between No. 2 Georgia and No. 4 Alabama. The Bulldogs are 2-point road favorites, per the latest Week 5 college football odds, despite the Tide being the only team to defeat the Dawgs over their last 51 games, and Bama did so twice. Other ranked matchups include No. 20 Oklahoma State vs. No. 23 Kansas State (-4.5), No. 15 Louisville vs. No. 16 Notre Dame (-6) and No. 9 Penn State vs. No. 19 Illinois (+17.5). Additionally, No. 1 Texas will contest its first SEC game as the Horns are favored by 39.5 points over Mississippi State in the Week 5 college football lines.

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