The NFL is back and the Week 2 NFL schedule will be highlighted by a showdown between superstar quarterbacks when the Kansas City Chiefs host the Cincinnati Bengals. Patrick Mahomes and Joe Burrow have gone head-to-head on four occasions, with Burrow getting the better of the exchange in three of those games. However, the Chiefs are 5.5-point favorites in the Week 2 NFL odds via the SportsLine Consensus. 

Meanwhile, the Cowboys are 6.5-point favorites in a big NFC matchup with the Saints and the Lions are 7.5-point favorites over the Buccaneers in a rematch of a divisional round battle last postseason. So who wins those games and what else do you need to know ahead of Week 2 in the NFL?