2024 NFL Playoffs 49ers vs. Packers odds, line: Advanced computer model reveals picks for Saturday's NFC Divisional Round game

The top-seeded San Francisco 49ers will try to continue their recent postseason dominance against Green Bay when they host the seventh-seeded Packers on Saturday in a 2024 NFC Divisional Round matchup. San Francisco (12-5) is 5-4 all-time against Green Bay in the NFL playoffs, but has won the last four meetings, including a 13-10 victory in the Divisional Round two years ago. The Packers (10-8) will try to end the slide after cruising to a shocking 48-32 victory at Dallas during Super Wild Card Weekend.

Kickoff at Levi's Stadium is scheduled for 8:15 p.m. ET. San Francisco is a 10-point favorite in the latest 49ers vs. Packers odds while the over/under for total points scored is 50.5. Before you make any Packers vs. 49ers picks or NFL playoff predictions, you need to see what the SportsLine Projection Model has to say.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the divisional round of the 2024 NFL playoffs on an incredible 183-129 run on top-rated NFL picks that dates back to the 2017 season. It also is on a 37-21 roll on top-rated picks since Week 7 of last season and nailed seven straight top-rated picks entering the 2024 NFL playoffs.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model knows San Francisco boasts ranked second in total offense (398.4 yards), third in both rushing (140.5 yards) and scoring (28.9 points) and fourth in passing (257.9 yards) during the regular season. Quarterback Brock Purdy proved he wasn't just a flash in the pan during his rookie year, finishing fifth in passing yards (4,280), third in touchdown tosses (31) and first in both passer rating (113.0) and QBR (72.7).

The model also knows Green Bay became the first No. 7 seed to record a win since the NFL playoff bracket expanded in 2020. Jordan Love completed 16-of-21 pass attempts for 272 yards and three touchdowns in his first career postseason game after finishing second in the NFL with 32 during the regular season. The 25-year-old quarterback has thrown 21 TD passes and just one interception over his last nine contests.

Now, the model has set its sights on 49ers vs. Packers. We can tell you the model is leaning Under the total, and it also says one side of the spread has ALL the value! You ABSOLUTELY need to see it before locking in any NFL picks.

So who wins 49ers vs. Packers on Saturday, and which side of the spread has ALL the value? ... Join SportsLine now to see which side of the Packers vs. 49ers spread to back, all from the model on an incredible 183-129 run!