2022 NCAA Tournament Murray State vs. Saint Peter's odds, predictions: College basketball lines, picks for Saturday by top model

After scoring a stunning upset over Kentucky in the first round of the 2022 NCAA Tournament, the Saint Peter's Peacocks will take on the Murray State Racers in a second-round matchup on Saturday. Both teams needed overtime to win their first-round matchups and now they'll go head-to-head for a spot in the East Regional semifinals. Saint Peter's is the No. 15 seed in the region and has a 20-11 record while Murray State is the No. 7 seed and is 31-2.

Tipoff is set for 7:45 p.m. ET at Gainbridge Fieldhouse in Indianapolis. The Racers are 8.5-point favorites in the latest Murray State vs. Saint Peter's odds from Caesars Sportsbook, and the Over-Under is set at 130. (Head over to our college basketball odds page for up-to-date odds on every game). 

Before you make any Saint Peter's vs. Murray State picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that Murray State's strength could be a problem for Saint Peter's after the Racers dominated the Dons on the glass in the first round. Murray State won the rebounding battle 42-32 and also showed its scoring versatility with five players reaching double-figures in the 92-87 OT win. Point guard Justice Hill initiated offense effectively and had 15 points, nine assists and five rebounds while OVC Player of the Year K.J. Williams had 18 points and seven rebounds. 

The model also knows that Saint Peter's is red-hot right now coming off a performance against Kentucky where it shot 50.9 percent from the field and 52.9 percent from the 3-point line. It was the Peacocks' eight win in a row and their defense has been stifling during this stretch. They've held opponents to just 32.7 percent shooting during their current win streak.

Now, the model has broken down the Murray State vs. Saint Peter's matchup from every angle and revealed its results. We can tell you the model is leaning Over on the total, and it also says one side of the spread hits in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Murray State vs. Saint Peter's in their 2022 NCAA Tournament opener? And which side of the spread hits well over 50 percent of the time? ... Join SportsLine right now to find out which side of the Saint Peter's vs. Murray State spread you should be all over Saturday, all from the model on a roll on college basketball picks!