The 2021 Final Four takes place on Saturday as top-seeded Baylor takes on second-seeded Houston in the first matchup at 5:14 p.m. ET. The nightcap sees overall No. 1 seed Gonzaga take on No. 11-seed UCLA at 8:34 p.m. ET. The Bears are five-point favorites and the over-under for total points scored is 135. Gonzaga is a 14-point favorite and the over-under is 145 in the latest 2021 Final Four odds from William Hill Sportsbook (see the latest lines for both games on our college basketball odds page).

Before locking in any college basketball picks for the Final Four, make sure you see what SportsLine senior analyst Larry Hartstein has to say. 

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach. This season, Hartstein has emerged as SportsLine's top overall college basketball analyst, posting a record of 216-165 heading into the Final Four for a massive profit of more than $3,400! Anyone who has followed him is WAY UP!

Now, Hartstein has crunched the numbers for Saturday's Final Four, with against-the-spread and over-under picks for both games. A successful parlay of these picks would pay out around 12-1!

We can tell you he's leaning Under 135 total points in Baylor vs. Houston. Hartstein has found a pair of key x-factors that has him ALL OVER the spread in both matchups. You ABSOLUTELY need to see what he's picking before you make any plays of your own.

So which Final Four teams cover? And which X-factors could lead to a MASSIVE 12-1 payout? ... Join SportsLine right now to see Larry Hartstein's Final Four for Saturday, all from the expert who's up more than $3,400 on his college basketball picks!