San Diego's players could be low on confidence after they lost 5-0 at home to Philadelphia Union last weekend. Their now ninth in the Western Conference, and their away record is poor - six defeats from 11 games on the road. Inter Miami beat Cruz Azul 2-0 in the Campeones Cup final on Wednesday, and the Herons are on a five-game unbeaten streak. Lionel Messi is still in fine form, so they should have too much firepower for San Diego to handle.

Nashville's home record is superb this season. They Boys and Gold have picked up 11 wins and a draw from 12 games at Geodis Park, which is why they're so far ahead of their rivals in the race for the Supporters' Shield. Chicago Fire's away record is also solid, but they're currently on a six-game winless streak, and they're also coming off a 2-1 defeat to New England.

Nashville SC has the best record in Major League Soccer this season. The Boys in Gold are 10 points clear of their closest rivals, Inter Miami, at the top of the Eastern Conference table. They’ve won all three games since MLS resumed in mid-August, beating Inter Miami 4-1, New York Red Bulls 1-0, and Columbus Crew 3-2. FC Cincinnati are also on an impressive unbeaten streak, but they still trail Nashville by 18 points in the Eastern Conference. This game will take place in Nashville, and home advantage could swing things in their favor. They have 10 wins and one draw from 11 home games, whereas Cincinatti has only won once in 10 games on the road.

Nashville SC has the best home record in Major League Soccer this season: nine wins, one draw, and zero defeats from 10 games. The Boys in Gold have scored 29 goals and conceded just 10 times at Geodis Park. They should be full of confidence after thumping Inter Miami 4-1 last weekend, before securing a midweek away win against New York Red Bulls. Columbus Crew have only won once in 10 away games this season, which doesn’t bode well for their chances of getting a result against Nashville.

Real Salt Lake have been superb at home this season. They've won seven of their eight MLS games at America First Field, and they beat Juarez 3-0 at home in the Leagues Cup in midweek. Minnesota United are a strong team, but they've struggled on the road this season. They've lost four of their nine away MLS games, and they haven't won on the road since early May.

This promises to be an entertaining game between two in-form teams. The Revs have won eight of their 10 home matches this season, and their games at Gillette Stadium have averaged 2.9 goals. Houston is unbeaten since the MLS season resumed last month, and the players should be full of confidence after beating Sporting KC 2-0 on the road last weekend. Their away games have averaged 3.75 goals this season, so this should be a high-scoring contest. Over 2.5 goals has paid off in their last six meetings, so it looks like a great option here.