Patriots vs Colts prediction, props, odds: Top-rated NFL expert reveals player prop bet picks for Week 15

A pivotal AFC matchup is on tap when Mac Jones and the New England Patriots (9-4) travel to Lucas Oil Stadium to take on Jonathan Taylor, Carson Wentz and the Indianapolis Colts (7-6) in a key Week 15 NFL game on Saturday, December 18. Kickoff is at 8:15 p.m. ET. Indianapolis is looking for a win to keep pace in the AFC playoff race, while New England is looking to continue its push towards locking up the conference's top seed. The Colts are favored by 2.5 points in the latest Patriots vs. Colts odds from Caesars Sportsbook, and the over-under is set at 45.5 points. In addition to the Colts vs Patriots point spread and Week 15 NFL betting lines, Caesars is also offering a plethora of prop bet options for this matchup between two of the AFC's top teams, and SportsLine expert R.J. White has just revealed his top plays.

Looking for expert advice to sharpen your betting skills? Or do you need an edge in your fantasy league? Sign up for the SportsLine Daily newsletter NOW to get sports picks and fantasy advice delivered directly to your inbox.

White, a CBS Sports fantasy and gambling editor, ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. He also enters Week 15 as SportsLine's No. 5 rated NFL expert, going 55-44-2 (+800) on his last 101 NFL ATS picks. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. Anyone who has followed his picks has seen HUGE returns.

You can see all of White's expert NFL picks and analysis HERE.

Now, White has locked in on Colts vs. Patriots and just revealed his top three prop bet picks for this Week 15 NFL matchup. He has two confident prop bet picks featuring big-name players for the Patriots, including Rookie of the Year front-runner Mac Jones. He's also made his call on an under the radar prop offering for Indianapolis. You absolutely need to see all of White's Week 15 NFL prop bet picks before locking in any bets of your own.

Which prop bets should you back in the Colts vs. Patriots matchup on Saturday night? And how well will NFL Offensive Rookie of the Year front-runner Mac Jones perform in this prime time matchup? ... Join SportsLine now to find out, all from the NFL expert who has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest!

Mac Jones Over 1.5 passing TDs (+115)

"With Jones coming off the injury report heading into this game, he should be able to handle a typical workload -- and by that, I don't mean three pass attempts like he had in his previous game against the Bills in extreme weather conditions. He's thrown multiple TDs five times this year and now squares off with a team that has given up 26 passing TDs to quarterbacks on the year. The NFL high? 27 passing TDs. That's compared to eight rushing TDs, the third best mark in the league. I still expect New England to have success on the ground, but I believe they'll take the optimal path of reaching the end zone via the rookie QB's arm more times than not."

Nyheim Hines Over 16.5 receiving yards (-115)

"Jonathan Taylor has been absolutely dominant in recent weeks, but that doesn't mean Hines has been kept off the field completely. He's seen at least four targets in five of the last six games and reached at least 17 yards in every game where he had that workload. He'll be up against a Patriots defense that allows the fourth most receiving yards to running backs in the league. And frankly, the Patriots probably want the ball in Hines' hands instead of Taylor's. With such a small number, we likely only need Hines' standard four targets to hit the Over."

Kendrick Bourne Over 37.5 receiving yards (+105)

"Bourne has emerged as one of the most underrated receivers in the league during his first season in New England. His catch rate has spiked to nearly 80% despite playing with a rookie quarterback, and he has routinely made game-changing plays in the passing game over the last few weeks. He topped this total in each of the team's three games prior to the Buffalo windstorm, and he's missed the market in only two games since Week 3 if you remove the Buffalo game. Kenny Moore is likely to make things tough on Jakobi Meyers in the slot, so I expect Bourne to be a big factor in the passing attack this week."

Looking for the best picks against the spread, sharp plays on the total, and props you can take straight to the pay window? Join Jonathan Coachman on the Early Edge as he speaks with SportsLine's top handicappers to preview the day's biggest games. We promise to keep it short, sweet and to put some green in your pocket. Early Edge is in your feed every single day by 11 a.m. ET. Subscribe right here on YouTube to watch daily, plus don't miss the Early Edge specials and live shows!