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NFL Preseason schedule 2021: Odds, picks, predictions, best bets, TV coverage for full Week 2 slate

Odds, picks, best bets, and TV coverage for every game on the Week 2 NFL Preseason schedule
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The NFL preseason 2021 schedule continues on with a full slate of games during Week 2. Monday Night Football returns this week with a matchup between the New Orleans Saints, who are trying to sort out a quarterback competition between Jameis Winston and Taysom Hill, and the Jacksonville Jaguars, who recently released Tim Tebow and also have a quarterback battle (between Trevor Lawrence and Gardner Minshew) on their hands. 

Other preseason games of note this week include the 49ers vs. Chargers, where fans will get a look at two promising young quarterbacks in Trey Lance and Justin Herbert; the Eagles vs. Patriots, which will give fans another look at New England rookie quarterback Mac Jones; and Packers vs. Jets, which will feature Zach Wilson, Aaron Rodgers, and Jordan Love (if his injury status improves). 

Here is a full rundown of the NFL preseason Week 2 games and TV schedule, as well as odds, picks, and predictions for several matchups. 

Which Fantasy Football sleepers, breakouts and busts should you target and fade? And which QB shocks the NFL with a top-five performance? Join SportsLine now to get 2021 Fantasy Football cheat sheets for every single position, all from the model that called Josh Allen's huge season.

New England Patriots vs. Philadelphia Eagles

  • Patriots vs. Eagles date and time: Thursday, August 19 at 7:30 p.m. ET
  • Patriots vs. Eagles spread: Patriots -1.5
  • Patriots vs. Eagles over-under: 38.5
  • Patriots vs. Eagles moneyline: Patriots -125, Eagles +105
  • Patriots vs. Eagles TV Coverage: NFL Network

Expert Eagles vs. Patriots picks HERE.

Kansas City Chiefs vs. Arizona Cardinals

  • Chiefs vs. Cardinals date and time: Friday, August 20 at 8 p.m. ET
  • Chiefs vs. Cardinals spread: Chiefs -2.5
  • Chiefs vs. Cardinals over-under: 41
  • Chiefs vs. Cardinals moneyline: Chiefs -140, Cardinals +120
  • Chiefs vs. Cardinals TV coverage: ESPN

Cincinnati Bengals vs. Washington Football Team

  • Bengals vs. Washington date and time: Friday, August 20 at 8 p.m. ET
  • Bengals vs. Washington spread: Washington -4.5
  • Bengals vs. Washington over-under: 34.5
  • Bengals vs. Washington moneyline: Washington -215, Bengals +185
  • Bengals vs. Washington TV coverage: NFL Network

Buffalo Bills vs. Chicago Bears

  • Bills vs. Bears date and time: Saturday, August 21 at 1 p.m. ET
  • Bills vs. Bears spread: Bears -5
  • Bills vs. Bears over-under: 38.5
  • Bills vs. Bears moneyline: Bills +190, Bears -220
  • Bills vs. Bears TV coverage: NFL Network

New York Jets vs. Green Bay Packers

  • Jets vs. Packers date and time: Saturday, August 21 at 4:25 p.m. ET
  • Jets vs. Packers spread: Jets -1.5
  • Jets vs. Packers over-under: 34
  • Jets vs. Packers moneyline: Jets -135, Packers +115
  • Jets vs. Packers TV coverage: NFL Network

Atlanta Falcons vs. Miami Dolphins

  • Falcons vs. Dolphins date and time: Saturday, August 21 at 7 p.m. ET
  • Falcons vs. Dolphins spread: Dolphins -5
  • Falcons vs. Dolphins over-under: 37
  • Falcons vs. Dolphins moneyline: Falcons +190, Dolphins -220
  • Falcons vs. Dolphins TV coverage: Local -- WFOR, WUPA

Baltimore Ravens vs. Carolina Panthers

  • Ravens vs. Panthers date and time: Saturday, August 21 at 7 p.m. ET
  • Ravens vs. Panthers spread: Ravens -3.5
  • Ravens vs. Panthers over-under: 35
  • Ravens vs. Panthers moneyline: Ravens -175, Panthers +155
  • Ravens vs. Panthers TV coverage: Local -- WSOC, WBAL

Detroit Lions vs. Pittsburgh Steelers

  • Lions vs. Steelers date and time: Saturday, August 21 at 7:30 p.m. ET
  • Lions vs. Steelers spread: Steelers -6.5
  • Lions vs. Steelers over-under: 37.5
  • Lions vs. Steelers moneyline: Lions +210, Steelers -250
  • Lions vs. Steelers TV coverage: NFL Network

Which Fantasy Football sleepers, breakouts and busts should you target and fade? And which QB shocks the NFL with a top-five performance? Join SportsLine now to get 2021 Fantasy Football cheat sheets for every single position, all from the model that called Josh Allen's huge season.

Tennessee Titans vs. Tampa Bay Buccaneers

  • Titans vs. Buccaneers date and time: Thursday, August 19 at 7:30 p.m. ET
  • Titans vs. Buccaneers spread: Buccaneers -2
  • Titans vs. Buccaneers over-under: 35
  • Titans vs. Buccaneers moneyline: Titans +100, Buccaneers -120
  • Titans vs. Buccaneers TV coverage: Local -- WTSP, WFTV, WKRN

Houston Texans vs. Dallas Cowboys

  • Texans vs. Cowboys date and time: Saturday, August 21 at 8 p.m. ET
  • Texans vs. Cowboys spread: Cowboys -4
  • Texans vs. Cowboys over-under: 37.5
  • Texans vs. Cowboys moneyline: Texans +165, Cowboys -185
  • Texans vs. Cowboys TV coverage: Local -- KTVT, KTRK

Indianapolis Colts vs. Minnesota Vikings

  • Colts vs. Vikings date and time: Saturday, August 21 at 8 p.m. ET
  • Colts vs. Vikings spread: Vikings -2.5
  • Colts vs. Vikings over-under: 38
  • Colts vs. Vikings moneyline: Colts +130, Vikings -150
  • Colts vs. Vikings TV coverage: Local -- KMSP, WXIN

Las Vegas Raiders vs. Los Angeles Rams

  • Raiders vs. Rams date and time: Saturday, August 21 at 10 p.m. ET
  • Raiders vs. Rams spread: Raiders -7
  • Raiders vs. Rams over-under: 35
  • Raiders vs. Rams moneyline: Raiders -300, Rams +250
  • Raiders vs. Rams TV coverage: NFL Network

Denver Broncos vs. Seattle Seahawks

  • Broncos vs. Seahawks date and time: Saturday, August 21 at 10 p.m. ET
  • Broncos vs. Seahawks spread: Broncos -5
  • Broncos vs. Seahawks over-under: 37.5
  • Broncos vs. Seahawks moneyline: Broncos -230, Seahawks +195
  • Broncos vs. Seahawks TV coverage: Local -- KING, KTVD

New York Giants vs. Cleveland Browns

  • Giants vs. Browns date and time: Sunday, August 22 at 1 p.m. ET
  • Giants vs. Browns spread: Browns -6
  • Giants vs. Browns over-under: 35.5
  • Giants vs. Browns moneyline: Giants +205, Browns -245
  • Giants vs. Browns TV coverage: NFL Network

San Francisco 49ers vs. Los Angeles Chargers

  • 49ers vs. Chargers date and time: Sunday, August 22 at 7:30 p.m. ET
  • 49ers vs. Chargers spread: 49ers -4.5
  • 49ers vs. Chargers over-under: 34
  • 49ers vs. Chargers moneyline: 49ers -230, Chargers +195
  • 49ers vs. Chargers TV coverage: NFL Network

Jacksonville Jaguars vs. New Orleans Saints

  • Jaguars vs. Saints date and time: Monday, August 23 at 8 p.m. ET
  • Jaguars vs. Saints spread: Saints -4
  • Jaguars vs. Saints over-under: 38.5
  • Jaguars vs. Saints moneyline: Jaguars +175, Saints -200
  • Jaguars vs. Saints TV coverage: ESPN

Which Fantasy Football sleepers, breakouts and busts should you target and fade? And which QB shocks the NFL with a top-five performance? Join SportsLine now to get 2021 Fantasy Football cheat sheets for every single position, all from the model that called Josh Allen's huge season.

SportsLine Staff