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    Sun, Nov 079:25 pm UTCLevi's Stadium
    62 F
    Track OnCBS Sports
    Arizona
    Cardinals
    ARI
    Last 5 ATS
    W/L11-6
    ATS10-7
    O/U8-9-0
    FINAL SCORE
    --
    -
    --
    San Francisco
    49ers
    SF
    Last 5 ATS
    W/L10-7
    ATS9-8
    O/U8-8-1
    SPREAD
    MONEYLINE
    OVER/UNDER
    Last 5 ATS
    11-6
    Win /Loss
    10-7
    10-7
    Spread
    9-8
    8-9-0
    Over / Under
    8-8-1
    Key Injuries
    Key Injuries
    Avatar
    DE
    Avatar
    OLB
    Avatar
    LS
    Key Injuries
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    NT
    Avatar
    LB
    Avatar
    SAF
    SPREAD
    MONEYLINE
    OVER/UNDER

    Simulation Picks

    SPREAD
    ARI @ SF
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    Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks!

    MONEYLINE
    ARI @ SF
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    OVER / UNDER
    ARI @ SF
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    0%
    PUBLIC
    0%
    MONEY
    0%
    PUBLIC
    0%
    MONEY
    Over0%
    PUBLIC
    Under0%
    Over
    MONEY
    Under

    Understanding Public and Money

    Read More

    Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

    Expert Picks

    Over / UnderUnder 45 -110
    LOSS
    Unit1.0
    +90
    2-1 in Last 3 SF O/U Picks
    Kenny's Analysis:

    Cardinals QB Kyler Murray is questionable for the game, as is WR DeAndre Hopkins. Arizona has the No. 2 defense in my ratings. San Francisco's defense is 11th. The 49ers will have QB Jimmy Garoppolo back under center after he missed the 17-10 loss at Arizona in Week 5, but it likely won't help get the total Over.

    Pick Made: Nov 07, 6:08 pm UTC
    Money LineSan Francisco -129
    LOSS
    Unit1.0
    +579
    19-9 in Last 28 NFL Picks
    +350
    4-0 in Last 4 SF ML Picks
    Matt's Analysis:

    The smart move probably is to wait until Sunday morning for this one, but it's my birthday weekend so doubt will be at a computer then and the spread might be much higher. This has flipped from Cards -3 to Niners -2 with Kyler Murray very questionable -- so is DeAndre Hopkins. If you watched TNF in Week 8, Hopkins couldn't even finish with his hammy and Murray was in major pain walking off following that crushing interception. Might they gut it out Sunday? Perhaps, but at way less than 100 percent. Plus, AJ Green is out in COVID as are a few assistant coaches. This sets up perfectly for the Niners, who got a little mojo back last week spanking my Bears. May as well take the moneyline at just 20 cents higher than Niners -2 to avoid any funny business.

    Pick Made: Nov 05, 8:26 pm UTC
    Point SpreadSan Francisco +1.5 -110
    LOSS
    Unit1.0
    +409
    25-19 in Last 44 NFL Picks
    +359
    29-23 in Last 52 NFL ATS Picks
    +910
    38-28 in Last 66 SF ATS Picks
    R.J.'s Analysis:

    With Arizona coming off its first loss of the season, this would typically shape up as a great bounce-back spot. But Kyler Murray seems to have a real chance of missing this game due to an ankle injury, while DeAndre Hopkins didn't practice to start the week with a hamstring issue, and A.J. Green was placed on the COVID list. Like last week, we want to be ahead of any potential Murray news before the line moves, though it didn't work out so well backing Minnesota. The 49ers should do a better job; they outgained Arizona in the first meeting between these teams with Trey Lance at QB. Look for the Niners as a teaser leg on this number too.

    Pick Made: Nov 03, 10:31 pm UTC
    Point SpreadSan Francisco PK -110
    LOSS
    Unit1.0
    +90
    2-1 in Last 3 NFL ATS Picks
    +190
    2-1 in Last 3 SF ATS Picks
    Jeff's Analysis:

    The 49ers bring in the better offensive and defensive lines at Football Outsiders. San Francisco's defensive line is ranked No. 5, while Arizona is 21st. Cardinals QB Kyler Murray (ankle) is questionable to start. I'm hearing Arizona wants to hold him out until he's 100 percent healthy. That won't be this week. In that case, Colt McCoy will start for the Cards. The 49ers lost 17-10 earlier this season, despite outgaining Arizona 338-304. 49ers coach Kyle Shanahan knows how to defend Murray in the event he starts. I think this is the perfect time to start fading Kliff Kingsbury and company. Shanahan is 8-4 SU and 8-4 ATS in revenge games over the past three years.

    Pick Made: Nov 03, 5:18 pm UTC
    Point SpreadArizona -2.5 -115
    WIN
    Unit1.0
    +190
    4-2 in Last 6 SF ATS Picks
    Allan's Analysis:

    I'll bite and bounce back with Arizona. The Cardinals are 4-0 ATS on the road this season and already defeated San Francisco just four short weeks ago. The 49ers have scored 21 points or fewer in three of its last four games and if we get the Kyler Murray revenge offense Sunday then I'm not sure San Francisco can play (and score) fast enough to keep up. Give me Arizona under 3.

    Pick Made: Nov 02, 6:10 am UTC

    Team Injuries

    Arizona Cardinals
    Tuesday, Mar 26, 2024
    Avatar
    OLB
    Kyzir White
    BicepsQuestionable
    Friday, Mar 08, 2024
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    DE
    L.J. Collier
    BicepsQuestionable
    Tuesday, Mar 05, 2024
    Avatar
    LS
    Matt Hembrough
    BackQuestionable
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    OG
    Jon Gaines II
    KneeQuestionable
    Avatar
    DT
    Dante Stills
    KneeQuestionable
    Avatar
    CB
    Garrett Williams
    AnkleQuestionable
    San Francisco 49ers
    Monday, Mar 25, 2024
    Avatar
    TE
    George Kittle
    GroinQuestionable
    Avatar
    CB
    Charvarius Ward
    GroinQuestionable
    Tuesday, Mar 05, 2024
    Avatar
    SAF
    Tayler Hawkins
    WristQuestionable
    Avatar
    DT
    Kalia Davis
    AnkleQuestionable
    Avatar
    TE
    Cameron Latu
    Knee - MeniscusQuestionable
    Avatar
    DE
    Drake Jackson
    KneeQuestionable
    Avatar
    WR
    Danny Gray
    Shoulder - AC JointQuestionable
    Tuesday, Feb 13, 2024
    Avatar
    NT
    Javon Hargrave
    ThumbQuestionable
    Avatar
    OT
    Nick Zakelj
    BicepsQuestionable
    Avatar
    SAF
    Talanoa Hufanga
    Knee - ACLQuestionable
    Monday, Feb 12, 2024
    Avatar
    LB
    Dre Greenlaw
    AchillesQuestionable