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Twins vs. Indians odds, lines: Advanced computer MLB model reveals picks for Wednesday's game

SportsLine's Projection Model generated a pick for Wednesday's MLB game between Minnesota and Cleveland

By@SportsLineUpdated: Apr 28, 2021 1:53PM UTC . 2 min read

The Cleveland Indians go for the three-game sweep when they take on the Minnesota Twins on Wednesday afternoon. First pitch is at 1:10 p.m. ET at Progressive Field in Cleveland. 

Minnesota is the -115 favorite (risk $115 to win $100) on the money line at William Hill Sportsbook, while the Over-Under for runs scored is 9 in the latest Twins vs. Indians odds (see up-to-date lines for every game on our MLB odds page). 

Before making any Twins vs. Indians picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. It is off to a profitable start in 2021, going 29-21 on top-rated MLB money-line picks through four weeks, returning over $250. Anyone following it has seen HUGE rewards!

Now, it has set its sights on Twins vs. Indians. We can tell you it's leaning Under, but it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

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