Garcia (elbow/neck/biceps) underwent thoracic outlet surgery Thursday and will miss the rest of the season, Arden Zwelling of Sportsnet.ca reports.
Abreu (5-3) earned the win Tuesday over the Yankees, allowing a run on three hits across one inning.
Pena went 2-for-5 with a two-run home run and an additional run scored during Tuesday's 9-7 win over the Yankees.
Lukes went 2-for-4 with a two-run single during the Blue Jays' 5-3 loss to the Royals on Tuesday.
Miles will serve as the opening pitcher during Wednesday's game against the Royals, Mitch Bannon of The Athletic reports.
Hader earned the save in Tuesday's 9-7 win over the Yankees, striking out one batter across 1.1 scoreless innings without allowing a hit or walk.
Pena went 2-for-5 with a two-run home run and an additional run score during Tuesday's 9-7 win over the Yankees.
Alvarez went 3-for-5 with an RBI triple and two runs scored during the Astros' 9-7 win over the Yankees on Tuesday.
Varsho went 2-for-5 with two RBI during the Astros' 9-7 win over the Yankees on Tuesday.
Pecko did not factor into the decision Tuesday against the Yankees, allowing five runs on five hits and four walks while striking out one batter over 4.1 innings.
Yordan Alvarez looks fully back from injury, with three 3-hit games over his last five played. Interestingly, he's been slightly better against LHPs than RHPs this season, despite being a left-handed hitter—though his career OPS splits are fairly even. Shane Bieber has dominated left-handed batters, but the sample size is just three games. Alvarez is 1-2 in his career against Bieber. We set Alvarez's line at +315 to homer.
