Triple-A Omaha placed Spence on its 7-day injured list Monday due to an unspecified injury.
Lynch will start Friday's game against the Cubs, and the Royals intend to give the left-hander an opportunity in the rotation moving forward, Anne Rogers of MLB.com reports.
The Cardinals outrighted Hence to the rookie-level Florida Complex League on Thursday.
The Cardinals claimed Pereira off waivers from the White Sox on Thursday.
The Royals transferred Avila (elbow) to the 60-day injured list Thursday.
The Royals claimed Little off waivers from the Cubs on Thursday and optioned him to Triple-A Omaha.
The Royals outrighted Velazquez to Triple-A Omaha on Wednesday.
Wetherholt went 1-for-3 with two walks, a two-run double and a run scored during the Cardinals' 3-1 win over the Yankees on Wednesday.
Pallante (12-6) earned the win against the Yankees on Wednesday, allowing one run on three hits and three walks while striking out four across 5.1 innings.
Cruz secured the save Wednesday against the Twins, throwing a clean ninth inning. He struck out one.
