This is the first game of an interesting interleague matchup. Cal Quantrill has been good recently but his underlying numbers are showing that he should regress soon. Adam Wainwright has been very good this season but the Cards bats are swinging well right now and they should only be helped by the DH. Take the Cards.

The Cardinals are eight games under .500 on the road overall, 6-16 in their past 22 away and have won just four of their past 15 series openers yet favored. Hmmm. They do add the DH. It's Adam Wainwright for the Redbirds. His road ERA is 5.35. Cleveland is 4-1 in its past five at home vs. the NL and starts underrated Cal Quantrill (3.84 ERA). He is 2-0 with a 3.22 ERA this month. We'll take the soon-to-be Guardians (still can't believe they chose that name) on the runline.

Cal Quantrill (2-2, 3.84 ERA) will look to continue his strong pitching when he takes the mound on Tuesday. Quantrill owns a 2-0 record with a 3.22 ERA in four starts in July after allowing one run on four hits in six innings of a no-decision versus Tampa Bay on Thursday. Adam Wainwright has an 5.35 ERA on the road this season. The Cardinals are 2-5 against the AL and 5-10 when playing after a day off this season. Take the home team.

My model says the Cardinals win in almost 70 percent of the simulations, so you're getting excellent value with them at this number. St. Louis RHP Adam Wainwright struggled in his first start after the All-Star break but bounced back by limiting the Chicago Cubs to one run over seven innings last Wednesday. The veteran won both of his previous career turns against Cleveland, tossing a complete game last season while yielding two runs in seven frames on June 9. Expect another strong effort from Wainwright and take the Cardinals.