The Philadelphia 76ers host the Washington Wizards in an Eastern Conference face-off at 7 p.m. ET on Wednesday. Philadelphia is favored by 10.5 points at home, while the Over-Under is set at 210.5 (see up-to-date odds for every game this week on our NBA odds page). Before making any Wizards vs. 76ers picks, you NEED to check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 16 of the 2021-22 NBA season on a stunning 62-32 roll on all top-rated NBA picks, returning over $2,500. Anyone following it has seen HUGE returns.

The model knows Washington is elite in a few key areas, headlined by fast break defense. The Wizards allow the fewest fast break points in the NBA, and Washington is No. 2 in the league in three-pointers allowed. Washington is also tremendous in putting pressure on the rim on the offensive side. The Wizards rank in the top four of the NBA in free throw attempts, points in the paint and two-point shooting accuracy.

The model also knows Philadelphia is potent on offense. The 76ers are scoring 111.2 points per 100 possessions this season, and Philadelphia commits a turnover on only 13.2 percent of possessions. Philadelphia has a strong shooting profile, including 46.4 percent from the field, 35.5 percent from three-point range and 81.1 percent from the free throw line. The 76ers are also facing a Washington team that is dead-last in the NBA in turnover creation and steals.

Now, it has set its sights on Wizards vs. 76ers. We can tell you the model is leaning over the total, and it also says one side of the spread hits in over 60 percent of simulations! You ABSOLUTELY need to see it before locking in any NBA picks.

Who wins Wizards vs. 76ers? And which side of the spread hits over 60 percent of the time? ... Join SportsLine right now to find out which side of the Wizards vs. 76ers spread you should be all over Wednesday, all from the model on a roll on NBA picks!