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    White Sox vs. Tigers lines, picks: Odds and predictions for teams' 2022 MLB season opener from advanced computer model

    SportsLine's Projection Model has generated picks for Friday's matchup between American League Central rivals Chicago and Detroit
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    The defending AL Central champion Chicago White Sox visit the Detroit Tigers on Friday as the teams begin their MLB seasons at Comerica Park. Right-hander Lucas Giolito is scheduled to start for Chicago, while lefty Eduardo Rodriguez is set to open for the Tigers.

    First pitch in Detroit is scheduled for 1:10 p.m. ET. Chicago is listed as a -140 favorite (risk $140 to win $100) on the money line in the latest White Sox vs. Tigers odds from Caesars Sportsbook, while the over-under for total runs scored is 7.5 (see the latest lines for every game on our MLB odds page).

    Before you consider any Tigers vs. White Sox picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

    This model, which simulates every game 10,000 times, enters the 2022 MLB season coming off a 209-178 record on top-rated MLB money-line picks in 2021, returning over $700 for $100 players. Anyone following it has seen HUGE returns!

    The model knows Chicago will be eager to get off to a fast start as it seeks to win consecutive division titles  for the first time in franchise history. Giolito is starting on Opening Day for the third straight year, and he allowed two runs on two hits and struck out eight last year. He left with a 3-2 lead, but the Angels scored two in the bottom of the eighth for a 4-3 victory. The White Sox averaged 4.9 runs per game last season, sixth in MLB, and also were sixth in run differential (plus-147). Jose Abreu had 30 homers and drove in 117 runs.     

    The model also has accounted for Detroit's additions and knows it is ready to make some noise with some solid young pieces. Rodriguez is one of many newcomers, and he went 64-49 with a 4.16 ERA and 1.31 WHIP in six seasons with the Red Sox, averaging 149 strikeouts per season. Shortstop Javier Báez (31 HR with Cubs and Mets) and outfielder Austin Meadows (106 RBI with Rays) will bolster a lineup of strong prospects. First baseman Spencer Torkelson, the 2020 first overall pick, is set to make his MLB debut.

    Now, the model has scrutinized the Tigers vs. White Sox matchup, and we can tell you the model is leaning Over and the total, and it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

    So who wins White Sox vs. Tigers? And which side of the money line has all the value? ... Join SportsLine right now to find out which side of the Tigers vs. White Sox money line you should be all over on Friday, all from the model that went 209-178 on top-rated MLB money-line picks in 2021!

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    SportsLine Staff

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