Two Big 12 teams looking to snap losing streaks meet for the first time this season on Wednesday night when Oklahoma visits West Virginia. Tip from WVU Coliseum is set for 8 p.m. ET, where the Mountaineers are 10-1 this season. The Sooners are 12-7, but have won just one of their four road games. West Virginia lost its last three games, each against ranked opponents, but Oklahoma has lost four-in-a-row; three of which were in the Top 25.

The Mountaineers are favored by two points in the latest West Virginia vs. Oklahoma odds from Caesars Sportsbook, and the over-under is set at 129.5. Before you make any Oklahoma vs. West Virginia picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

Now, it has simulated West Virginia vs. Oklahoma 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins West Virginia vs. Oklahoma? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks ... If you're already a member, see the picks below!