No. 22 Iowa State looks to continue to keep pace with the teams at the top of the Big 12 standings on Saturday when it takes on West Virginia on Saturday. The Cyclones are in a three-way tie for second place with No. 15 Oklahoma State and No. 16 Baylor, and enters the weekend on a three-game winning streak. West Virginia pulled out its first win in four games last weekend with a 29-17 win against TCU.

Kickoff for the game happens at at 2 p.m. ET from Mountaineer Field at Milan Puskar Stadium. The Cyclones are favored by seven points in the latest West Virginia vs. Iowa State odds from Caesars Sportsbook, and the over-under is set at 48. Before you make any Iowa State vs. West Virginia picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of $3,900 for $100 players on its top-rated college football picks against the spread. It also enters Week 9 of the 2021 season on a 26-11 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated West Virginia vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins West Virginia vs. Iowa State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!