The Syracuse Orange welcome the Virginia Cavaliers to the JMA Wireless Dome for an ACC battle at 7 p.m. ET on Friday. Syracuse is favored by 10 points at Caesars Sportsbook, while the over/under is set at 54 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Virginia vs. Syracuse picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

The model knows Virginia is generating quality offense. The Cavaliers are averaging 413.3 yards per game, with a pair of games with at least 500 total yards. Virginia is above-average on the ground, averaging almost 180 yards per game, and veteran quarterback Brennan Armstrong has more than 1,000 career rushing yards to go along with his passing proficiency. 

The model has also factored in that Syracuse is 3-0 this season and playing at a high level. Running back Sean Tucker led the ACC with 1,496 yards last season, and he has more than 370 total yards to begin the 2022 season. Quarterback Garrett Shrader is also off to a strong start, generating more than 900 total yards and 11 touchdowns in three games.

Now, it has set its sights on Virginia vs. Syracuse. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in almost 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Virginia vs. Syracuse? And which side of the spread hits in almost 60% of simulations? ... Join SportsLine right now to find out which side of the Virginia vs. Syracuse spread you should be all over Friday, all from the model on a roll on college football picks!