Virginia vs. Ohio odds, lines: Proven model reveals college basketball picks for the 2021 NCAA Tournament first-round game

The fourth-seeded Virginia Cavaliers square off with the No. 13 seed Ohio Bobcats in Saturday's West Region first-round game of the NCAA Tournament in Bloomington, Ind. Tip-off is at 7:15 p.m. ET at Assembly Hall. The winner advances to play either Creighton or UC Santa Barbara. 

William Hill Sportsbook lists the Cavaliers as seven-point favorites, while the Over-Under for total points scored is 130.5 in the latest Virginia vs. Ohio odds (see up-to-date lines for every game on our college basketball odds page). 

Before making any Ohio vs. Virginia picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of over $2,500 for $100 players on its top-rated college basketball picks against the spread. It has also returned almost $500 on all top-rated college basketball picks this season. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on Virginia vs. Ohio. We can tell you the model is leaning Over the total, and it also says one side of the spread hits over 60 percent of the time! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Virginia vs. Ohio? And which side of the spread hits over 60 percent of the time? ... Join SportsLine right now to find out which side of the Virginia vs. Ohio spread you should be all over Saturday, all from the model on a roll on college basketball picks!