The Virginia Tech Hokies will take on the No. 25 Xavier Musketeers at 7 p.m. ET on Friday at Barclays Center in the 2021 Upsie NIT Season Tip-Off. The Musketeers are 4-1 while Virginia Tech is 5-1. The Hokies are favored by 3 points in the latest Virginia Tech vs. Xavier odds from Caesars Sportsbook, and the over-under is set at 135.5. Before you make any Xavier vs. Virginia Tech picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,100 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Virginia Tech vs. Xavier 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Virginia Tech vs. Xavier? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!