VCU vas. Saint Louis odds, prediction: 2026 Atlantic 10 Conference men's college basketball picks from proven model

The No. 18 Saint Louis Billikens will look to get back on track after having their 18-game winning streak snapped when they battle the VCU Rams in a key Atlantic 10 Conference matchup on Friday. VCU is coming off an 89-75 win over George Washington, while Saint Louis dropped an 81-76 decision at Rhode Island on Tuesday. The Rams (21-6, 12-2 A-10) can overtake Saint Louis for first place with a win. They have won 10 in a row. The Billikens (24-2, 12-1 A-10), who have won 19 games by double digits this season, are 16-0 on their home floor.

Tip-off from Chaifetz Arena in St. Louis is set for 7 p.m. ET. VCU leads the all-time series 17-7, but Saint Louis earned a 71-62 win on Jan. 7. Saint Louis is a 8.5-point favorite in the latest VCU vs. Saint Louis odds from DraftKings Sportsbook, while the over/under for total points scored is 166.5. 

Before making any VCU vs. Saint Louis picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 16 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 13-7 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated VCU vs. Saint Louis 10,000 times and the results are in. The model is leaning Under, and it also says one side of the spread hits over 50% of the time!

So who wins VCU vs. Saint Louis, and which side of the spread hits over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!