USMNT vs. Paraguay odds, predictions: 2026 World Cup picks from proven soccer expert

The highly-anticipated USMNT World Cup opener comes on Friday, June 12, as the Americans take on Paraguay in a Group D matchup at Los Angeles Stadium. The Americans are co-hosting the 2026 World Cup alongside Mexico and Canada, and they are the +125 favorites to win Group D. Paraguay, meanwhile, are +420 longshots to win Group D, but do have favorable odds (-190) to qualify for the knockout round.

Kickoff is 9 p.m. ET. The latest USA vs. Paraguay odds from FanDuel Sportsbook list the USMNT at -105 (risk $105 to win $100) on the 90-minute money line, with Paraguay at +310 and a draw at +230. The over/under for total goals is 2.5.

Before locking in any Paraguay vs. USA picks or World Cup 2026 predictions, you need to see what proven soccer expert Jon Eimer has to say.

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Champions League, Serie A, the FA Cup, and much more. He's been red-hot on his soccer betting picks in 2026, posting a 31-13-2 record and returning over $1,200 of profit on his Champions League picks. Anyone following could have seen HUGE returns!

Now Eimer has turned his attention to USA vs. Paraguay in the 2026 World Cup, and revealed his best bet.

One of Eimer's picks: He likes the Under 2.5 total goals in this one. 

"Paraguay have their captain Gustavo Gomez holding down the defense with over 85 International matches under his belt," Eimer said. "Their manager Alfaro plays a very defensive style of football, and will cause trouble for all teams in Group D."

Eimer has locked in his best bet, and it brings a plus-money return! Be sure to see what it is before locking in any picks of your own. 

What is the best bet for USA vs. Paraguay? ... Join SportsLine now to see Jon Eimer's best bet for Paraguay vs. USA, all from the soccer expert who went 31-13 on UCL picks!