Israel Adesanya defends his middleweight title against third-ranked contender Marvin Vettori in the main event of UFC 263 on Saturday night. The main card is set for 10 p.m. ET at Gila River Arena in Glendale, Ariz. Adesanya is a -240 favorite (risk $240 to win $100), while Vettori is offered at +200 (risk $100 to win $200) in the latest William Hill Sportsbook odds for UFC 263. 

Before making any UFC 263 picks of your own, you NEED to see the latest MMA predictions from SportsLine MMA analyst Kyle Marley. Over the past 27 months, $100 bettors who have followed Marley's picks are up more than $17,000. The accomplished MMA analyst has seen memorable run in 2020 carry over into 2021. He has now nailed 32 of his last 50 UFC main-event picks, a stretch that included a streak of five consecutive underdogs!

At UFC Fight Night last weekend, Marley's winners included calling for a win by Roman Dolidze (-140) against Laureano Staropoli (+120) in a light heavyweight battle on the main card.  Dolidze took a unanimous decision to give Marley's followers another easy winner. Anyone who has followed Marley is WAY UP! 

This week at UFC 263, we can tell you Marley is backing Jake Collier (+150) to pull the upset of Carlos Felipe (-170) in a heavyweight battle on the preliminary card. He's also backing one fighter to "pick up a spilt decision in an action-packed bout"! You ABSOLUTELY need to see Marley's other UFC 263 picks before making any of your own.

Who wins Adesanya vs. Vettori 2 and every bout on the UFC 263 card? And which fighter is a MUST-BACK? ... Join SportsLine right now to see which fighters you need to be all over Saturday, all from the expert who's up more than $17,000 on MMA picks!