The Jacksonville Jaguars will battle the Tennessee Titans with the AFC South title on the line at 8:15 p.m. ET on Saturday. Jacksonville is favored by 6.5 points at Caesars Sportsbook, while the over/under is 40. Before making any Titans vs. Jaguars picks, you NEED to check out the NFL predictions from the SportsLine Projection Model..

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2022 NFL season on an incredible 160-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 14-6 roll on top-rated NFL picks since Week 7 of this season. 

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

The model knows Jacksonville is averaging 365.8 total yards per game (No. 8), and that jumps to more than 400 in the last four games. The Jaguars are averaging 24.0 points per game this season and also beat the Titans on the road in the first matchup between the teams.

The model also knows the Titans are elite in run defense. Tennessee is allowing only 80.5 rushing yards per game (No. 2) and 3.4 yards per carry. The Titans have yielded only nine rushing touchdowns this season and opponents are converting fewer than 34% of third down chances.

Now, it has set its sights on Titans vs. Jaguars. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in well over 50% of simulations! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins Titans vs. Jaguars? And which side of the spread hits in well over 50% of simulations? ... Join SportsLine right now to find out which side of the Titans vs. Jaguars spread you should be all over Saturday, all from the model on a 160-113 roll on NFL picks!