Texas Tech vs. Oklahoma odds, line, spread: Proven model reveals college basketball picks, predictions for Feb. 22, 2022

A Big 12 battle is on tap between the No. 9 Texas Tech Red Raiders and the Oklahoma Sooners at 8 p.m. ET on Tuesday at United Supermarkets Arena. The Red Raiders are 21-6 overall and 16-0 at home, while Oklahoma is 14-13 overall and 2-7 on the road. Texas Tech is ranked third in the Big 12; Oklahoma is ranked ninth. 

The Red Raiders are favored by 10 points in the latest Texas Tech vs. Oklahoma odds from Caesars Sportsbook, while the over-under is set at 130.5. Before you make any Oklahoma vs. Texas Tech picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Texas Tech vs. Oklahoma 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Texas Tech vs. Oklahoma? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.