We've got another exciting ACC matchup on schedule as the Syracuse Orange and the Notre Dame Fighting Irish are set to tip at noon ET on Saturday at JMA Wireless Dome. Syracuse is 17-10 overall and 12-2 at home, while Notre Dame is 10-16 overall and 2-7 on the road. Syracuse is favored by 6 points in the latest Syracuse vs. Notre Dame odds, and the over/under is 133.5 points.

Before entering any Syracuse vs. Notre Dame picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 16 of the 2023-24 season on a 136-89 roll on all top-rated college basketball picks dating back to last season, returning nearly $2,500 for $100 players. It is also off to a sizzling 25-13 start on top-rated spread picks this season. Anyone following has seen huge returns.

The model has simulated Syracuse vs. Notre Dame 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50% of simulations.

So who wins Syracuse vs. Notre Dame, and which side of the spread hits more than 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!