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Steelers vs. Lions odds, line, spread: Proven model reveals NFL picks, predictions for Week 10, 2021

The SportsLine Projection Model simulated the Week 10 game between Detroit and Pittsburgh 10,000 times
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The Pittsburgh Steelers will take on the Detroit Lions at 1 p.m. ET on Sunday at Heinz Field. The Steelers are 5-3 overall and 3-2 at home, while Detroit is 0-8 overall and 0-4 on the road. 

Pittsburgh is favored by eight points in the latest Steelers vs. Lions odds from Caesars Sportsbook, and the over-under is set at 42.5. Before you make any Lions vs. Steelers picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up almost $7,600 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 10 of the 2021 season on an incredible 128-88 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY up.

Now, it has simulated Steelers vs. Lions 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Steelers vs. Lions? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks... If you're already a member, see the picks below!

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SportsLine Staff