The SMU Mustangs will take on the North Texas Mean Green at 7 p.m. ET on Saturday at Gerald J. Ford Stadium. The Mustangs are 1-0 after defeating Abilene Christian in Week 1, while North Texas is 1-0 after topping Northwestern State. The Mean Green ended last year fourth in the West Division of Conference USA, while SMU ended up third in the American Athletic's West Division.

The Mustangs are favored by 21 points in the latest SMU vs. North Texas odds from Caesars Sportsbook, and the over-under is set at 73. Before you make any North Texas vs. SMU picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 2 of the 2021 season on a 63-45 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated North Texas vs. SMU 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that hits in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins SMU vs. North Texas? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!