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Red Sox vs. Cardinals odds, line, prediction: 2026 MLB picks for Saturday, April 11 from proven model

SportsLine's projection model, which went 35-29 roll on top-rated MLB money-line picks last season, has locked in its MLB picks for Cardinals vs. Red Sox on Saturday

By@Daniel_LewisSLUpdated: Apr 11, 2026 8:49AM UTC . 2 min read

An interleague matchup between teams that have had opposing starts to the season unfolds Saturday night when the Boston Red Sox travel to take on the St. Louis Cardinals. Boston is off to a slow 4-9 start, while St. Louis has exceeded expectations thus far as the Cardinals are 8-5. Ranger Suarez (0-1, 8.64 ERA) is on the hill for Boston, while the Cardinals will counter with Kyle Leahy (1-1, 5.40 ERA).

First pitch from Busch Stadium is set for 7:15 p.m. ET. Boston is a -141 favorite (risk $141 to win $100) on the money line, while the over/under is 8.

Before making any Red Sox vs. Cardinals picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It was a profitable 35-29 on top-rated MLB money-line picks last season. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following could have seen strong returns!

The model has simulated this matchup 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

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