The Houston Astros will look to stay unbeaten in the postseason as they seek their second World Series title since 2017 when they take on the Philadelphia Phillies in Game 1 on Friday night. The Astros (106-56) are 7-0 in the playoffs after sweeps of Seattle and the New York Yankees. Nearly as hot are the Phillies (87-75), who are 9-2 in the postseason. Philadelphia is seeking its first World Series title since 2008. Aaron Nola will start Game 1 for Philadelphia, while Justin Verlander will be on the hill for Houston. 

First pitch from Minute Maid Park in Houston is set for 8:03 p.m. ET. Houston is listed as a -170 favorite (risk $170 to win $100) on the money line in the latest Phillies vs. Astros odds from Caesars Sportsbook, while the over/under for total runs scored is 6.5 (see the latest lines for every game on our MLB odds page).

Before making any Phillies vs. Astros picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it enters the 2022 World Series on a 20-13 roll on top-rated MLB money-line picks, returning more than $400. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen HUGE returns!

The model knows Houston shortstop Jeremy Peña helps power the offense. He went 2-for-4 with a homer, three RBI and two runs scored in Sunday's series clincher at New York. Peña batted .353 in the ALCS and has had two hits or more in three of seven postseason games. During the regular season, Peña hit .253 with 22 homers, 63 RBI and 72 runs scored. In two career games against Philadelphia, Peña is batting .333 with a homer and two RBIs.

The model also knows Philadelphia designated hitter Bryce Harper is on a 10-game hitting streak this postseason, including seven multi-hit games. He has five homers in the playoffs. Harper was on a tear in the NLCS, hitting .400 against the Padres. He went 8-for-20 with three doubles, two homers and five RBI. For the season, Harper was limited to 99 games due to injury, but still batted .286 with 18 homers, 65 RBI and 63 runs scored.

Now, it has set its sights on Phillies vs. Astros. We can tell you the model is leaning Over on the total, and it also says one side of the money line has ALL the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins World Series Game 1 Phillies vs. Astros? And which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the Phillies vs. Astros run line you should be all over on Friday, all from the model on a roll on MLB picks!